In response to neuroscience and scanning breakthroughs showing effects of isolation, rejection and despair on the brain, researchers have developed the "self-esteem initiative", including video games that aim to trick the brain into forming more positive mental images.
Diversity/Isolation -
there appears to be a growing trend towards "lifestyle tribes" - cut-off pockets of like-mindedness within towns and cities - of people who share the same ways of life, beliefs and political views.